Optimization of database tables in mysql is a process which has to be carried out regularly to make your database in good health.
According to mysql manual,
OPTIMIZE TABLE should be used if you have deleted a large part of a table or if you have made many changes to a table with variable-length rows (tables that have VARCHAR, VARBINARY, BLOB, or TEXT columns). Deleted rows are maintained in a linked list and subsequent INSERT operations reuse old row positions. You can use OPTIMIZE TABLE to reclaim the unused space and to defragment the data file.